Seminal angiotensin II type 2 receptor (AT2R) as a new biomarker for idiopathic Oligo-asthenozoospermia
نویسندگان
چکیده
منابع مشابه
P-218: Investigation of Association between Angiotensin II Type 1 and 2 Receptor (AT1R & AT2R) Gene Polymorphisms and Susceptibility to Pre-Eclampsia (PE) in Iranian Women
Background: Hypertension during pregnancy period along with the presence of protein in the urine, after the 20th weeks of gestation is called preeclampsia (PE). About five percent of all pregnancies are manifested with PE and its exact etiology has still remained unknown. The renin-angiotensin system (RAS) has an important role in the regulation of blood pressure during pregnancy and so pathoph...
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See Original cOntributiOn page 237 T he renin–angiotensin system is causally involved in a broad spectrum of cardiovascular diseases. Most of the known physiological and pathophysiological effects of angiotensin II are mediated by the angio tensin IItype 1 (AT1) receptor. The angiotensin IItype 2 (AT2) receptor is predominantly expressed in fetal and neonatal issues, is normally present only...
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All well-known deleterious effects of angiotensin (Ang) II, including vasoconstriction, inflammation, water and salt retention, and vascular remodeling, are mediated via its type 1 (AT1) receptor. This explains why AT1 receptor blockers (ARBs) and inhibitors of Ang II synthesis, such as ACE inhibitors and renin inhibitors, are beneficial for cardiovascular disease. Yet, Ang II has a second rece...
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Angiotensin II type 2 (AT2R) or bradykinin B2 (B2R) receptor activation enhances NO production. Recently, we demonstrated enhancement of NO production when AT2R and B2R are simultaneously activated in vivo. However, the mechanism involved in this enhancement is unknown. Using confocal fluorescence resonance energy transfer microscopy, we report the distance between the AT2R and B2R in PC12W cel...
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ژورنال
عنوان ژورنال: The Egyptian Journal of Hospital Medicine
سال: 2023
ISSN: ['1687-2002', '2090-7125']
DOI: https://doi.org/10.21608/ejhm.2023.291444